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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SIPA1L1 All Species: 22.42
Human Site: S388 Identified Species: 61.67
UniProt: O43166 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43166 NP_056371.1 1804 200029 S388 S F S S P M G S T E D L N S K
Chimpanzee Pan troglodytes XP_510040 1804 199959 S388 S F S S P M G S T E D L N S K
Rhesus Macaque Macaca mulatta XP_001084201 1804 200030 S388 S F S S P M G S T E D L N S K
Dog Lupus familis XP_537502 1806 199834 S388 S F S S P M G S T E D L N S K
Cat Felis silvestris
Mouse Mus musculus Q8C0T5 1782 197013 S388 S F S S P M G S T E D L N S K
Rat Rattus norvegicus O35412 1822 201906 S388 S F S S P M G S T E D F N S K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZMV8 730 80773
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A5PF44 1015 114125
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785253 1625 180489 K295 S P A P P Q F K Q L I Q G R V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 99.5 96.9 N.A. 94.6 93.3 N.A. N.A. 20.2 N.A. 21.1 N.A. N.A. N.A. N.A. 32.6
Protein Similarity: 100 99.9 99.7 98.5 N.A. 97 95.7 N.A. N.A. 28.6 N.A. 33.4 N.A. N.A. N.A. N.A. 49.5
P-Site Identity: 100 100 100 100 N.A. 100 93.3 N.A. N.A. 0 N.A. 0 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 100 100 N.A. 100 93.3 N.A. N.A. 0 N.A. 0 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 67 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 67 0 0 0 0 0 % E
% Phe: 0 67 0 0 0 0 12 0 0 0 0 12 0 0 0 % F
% Gly: 0 0 0 0 0 0 67 0 0 0 0 0 12 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 12 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 12 0 0 0 0 0 0 67 % K
% Leu: 0 0 0 0 0 0 0 0 0 12 0 56 0 0 0 % L
% Met: 0 0 0 0 0 67 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 67 0 0 % N
% Pro: 0 12 0 12 78 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 12 0 0 12 0 0 12 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 % R
% Ser: 78 0 67 67 0 0 0 67 0 0 0 0 0 67 0 % S
% Thr: 0 0 0 0 0 0 0 0 67 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _